I’m a big fan of speed and offline access, and most of this is solved with my daily driver, Mimestream.

Mimestream is a powerful email client designed specifically for Gmail users on Mac. It provides a native and streamlined experience for managing your emails with a focus on speed, reliability and ease of use with a native interface.

I still use Gmail from time to time, in part because its integrations with extensions and other tools is super deep. But when it comes to clearing spam with low latency and auto-advance, Mimestream is king.